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Metronidazole Tablet

Metronidazole Tablets, Indications for the Treatment of Intestinal and Intestinal Amoeba Disease (Such As Amoeba Liver Abscess, Pleural Amoeba Disease, Etc.).
  • Brand:

    BBCA PHARMA
  • Item NO.:

    C6H9N3O3
  • Order(MOQ):

    5000000
  • Goods Stock:

    50000000
  • Payment:

    L/C, T/T, DP
  • Product Origin:

    China (Mainland)
  • Color:

    White tablet
  • Shipping Port:

    Any Port in China
  • Lead Time:

    30 Days After Payment
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Product Detail

E-mail: lilyoo@bbcapharma.com

Methyl nitrosine tablets, adaptive to be used to treat intestinal and intestinal amoeba disease (e.G. Amoeba liver abscess, pleural amoeba, etc.). It can also be used to treat vaginal trichomoniasis, pouch disease and skin leishmaniasis, guinea worm infections, etc. It is also widely used in the treatment of anaerobic infection.

Warning

It is strictly prohibited for food and feed processing.

Ingredient

Ingredients: methazole.

Chemical name: 2-methyl-5-nitromiquinone-1-ethanol.

Chemical structure:

Molecular: C6H9N3O3

Molecular weight: 171.16

Characters

This product is white or white.

Indications

Used to treat intestinal and intestinal amoeba disease (e.G. Amoeba liver abscess, pleural amoeba, etc.). It can also be used to treat vaginal trichomoniasis, pouch disease and skin leishmaniasis, guinea worm infections, etc. It is also widely used in the treatment of anaerobic infection.

Specification

250mg / 500mg

E-mail: lilyoo@bbcapharma.com

Usage Usage

1. Adult commonly used amount

(1) intestinal amoeba disease, 0.4 to 0.6g (2-3 tablets), 3 times a day, course 7 days;

(2) jady worm disease, 0.4g (2 tablets) at a time, 3 times a day, treatment 5 to 10 days.

(3) guinea worm disease, 0.2 (1 tablet) g at a time, 3 times a day, treatment 7 days.

(4) pouch disease, 0.2g (1 tablet) at a time, 2 times a day, 5 days of treatment.

(5) skin leishmaniasis, 0.2g (1 tablet) at a time, 4 times a day, 10 days of treatment. Repeat one course after the interval of 10 days.

(6) trichomoniasis, 0.2g (1 tablet) at a time, 4 times a day, treatment for 7 days;

(7) anaerobic infection, oral daily 0.6 to 1.2g (3-6 tablets), divided into 3 times, 7 to 10 days for a course of treatment.

2, the common amount of children

(1) amoeba disease, daily weight of 35 to 50 mg / kg, divided into 3 oral, 10 days for a course of treatment.

(2) jadi worm disease, daily weight of 15 to 25 mg / kg, divided into 3 oral, even take 10 days;

(3) anaerobic infection, oral daily weight of 20 to 50 mg /kg.

Adverse Reactions

15% to 30% of cases of adverse reactions to the digestive tract reactions are most common, including nausea, vomiting, loss of appetite, abdominal cramps, generally do not affect treatment; a few cases of urticaria, redness, itching, cystitis, difficulty urinating, metallic taste in the mouth and white blood cell reduction, etc. , Are reversible, after discontinuation of the drug self-recovery.

E-mail: lilyoo@bbcapharma.com

Taboo

People with active central nervous system disorders and blood disorders are disabled.

Precautions

(1) interference with diagnosis: the metabolites of this product can make the urine appear crimson.

(2) the dose of the original liver disease patients should be reduced. Stop medication in the event of movement disorders or other central nervous system symptoms. White blood cell counts should be done before repeating a course of treatment. In patients with anaerobic infection with combined renal failure, the interval between administration should be extended from 8 hours to 12 hours.

(3) this product can inhibit the metabolism of alcohol, during the use of drugs should abstain from alcohol, drinking may appear abdominal pain, vomiting, headache and other symptoms.

Medication for Pregnant and Lactating Women

It is prohibited for pregnant and lactating women.

Children's Medicine

Refer to usage.

Medication for the Elderly

It is not clear.

Drug Interactions

This product can enhance the role of anticoagulant drugs such as warfarin. Combined with tomycin can interfere with the role of methyl nitrosium in removing vaginal trichomoniasis.

E-mail: lilyoo@bbcapharma.com

Drug Overdose

High doses can cause convulsions.

Pharmacological Toxicology

This product is a nitromiquine derivative, which can inhibit the redox reaction of amoeba protozoa and cause the nitrogen chain of the protozoa to break. In vitro tests have shown that when the concentration of the drug is 1 to 2 mg/l, the dissolved tissue amoeba can be changed in 6 to 20 hours, all killed within 24 hours, the concentration is 0.2 mg/l, and within 72 hours the dissolved tissue amoeba can be killed. This product has a powerful role in killing trichomoniasis, its mechanism is not clear.

Methyl nitrosine has an annihilation effect on anaerobic microorganisms, and the metabolites it produces when reduced in the human body also have anti-anaerobic bacteria, inhibiting the synthesis of dnaic acid of bacteria, thus interfering with the growth and reproduction of bacteria, and ultimately leading to bacterial death.

It has carcinogenic effects on some animals.

Pharmacokinary Dynamics

Oral or rectal administration can be quickly and completely absorbed, protein binding rate of 5%, widely distributed in tissues and body fluids, and through the blood-brain barrier, the effective concentration of drugs can appear in saliva, placenta, bile, milk, amniotic fluid, urine, pus and cerebrospinal fluid. It has been reported that the concentration of the drug in the placenta, milk, bile is similar to the concentration of blood drugs. The concentration of blood drugs in cerebrospinal fluid in healthy people was 43% of the concentration of blood drugs in the same period. In a small number of patients with cerebral abscesses, the concentration of the drug (34 to 45 mg/l) of the pus was higher than that of the same period (11 to 35 mg/l) after taking 1.2 to 1.8 g daily. The concentration of the drug in the pus after an infection in the ear is above 8.5 mg/l. After oral 1 to 2 hours blood concentration reached a peak, effective concentration can be maintained for 12 hours. Oral concentrations of 0.25g, 0.4g, 0.5g and 2g were 6, 9, 12, 40 mg/l, respectively. This product is excreted by the kidneys 60-80%, about 20% of the original drug excreted from the urine, the rest of the metabolites (25% glucoaldehyde acid bindings, 14% for other metabolic bindings) form by urine excretion, 10% with feces excretion, 14% excretion from the skin.

E-mail: lilyoo@bbcapharma.com

Storage

Blackout, sealed and saved.

Wrap

Oral solid medicinal high density polyethylene bottles 100 tablets per bottle.

Expiration Date

24 months.

Enforce the Standard

The 2010 edition of the chinese pharmacopoeia.

E-mail: lilyoo@bbcapharma.com

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